WFS1:Ensemblv115

wolframin ER transmembrane glycoprotein
OMIM: 606201, ClinGen, DECIPHER

11 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 11 panels
Green WFS1 in Cataract Level 2: Ophthalmological disorders Version 1.0	1 review	BIALLELIC, autosomal or pseudoautosomal	Sources Expert list Expert Review Green Phenotypes Wolfram syndrome 1, MIM# 222300
Green WFS1 in Optic Atrophy Level 2: Ophthalmological disorders Version 2.0	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Victorian Clinical Genetics Services Expert Review Green Phenotypes Wolfram syndrome 1, autosomal recessive, MIM# 222300 Wolfram-like syndrome, autosomal dominant, MIM#614296
Green WFS1 in Regression Level 2: Neurology and neurodevelopmental disorders Version 1.0	0 reviews	Unknown	Sources Expert Review Green Victorian Clinical Genetics Services
Green WFS1 in Deafness_IsolatedAndComplex Level 2: Hearing and ear disorders Version 2.0	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Victorian Clinical Genetics Services Melbourne Genomics Health Alliance Deafness Flagship Expert Review Green Phenotypes Deafness, autosomal dominant 6/14/38, MIM# 600965 Wolfram syndrome 1 222300 Wolfram-like syndrome, autosomal dominant, MIM# 614296
Red WFS1 in Maturity-onset Diabetes of the Young Level 2: Endocrine disorders Version 2.0	2 reviews	Unknown	Sources Other Expert Review Red Phenotypes maturity-onset diabetes of the young MONDO:0018911
Green WFS1 in Monogenic Diabetes Level 2: Endocrine disorders Version 1.0	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Phenotypes Wolfram-like syndrome, autosomal dominant, 614296 Wolfram syndrome, 222300 Deafness, autosomal dominant 6/14/38, 600965 ?Cataract 41,116400 {Diabetes mellitus, noninsulin-dependent, association with}, 125853 Deafness,autosomal dominant 6/14/38, 600965 {Diabetes mellitus, noninsulin-dependent,association with} diabetes insipidus or optic atrophy
Green WFS1 in Syndromic Retinopathy Level 2: Ophthalmological disorders Version 1.0	2 reviews	Unknown	Sources Expert Review Green RetNet
Green WFS1 in Mackenzie's Mission_Reproductive Carrier Screening Level 2: Screening Version 1.0	0 reviews	BIALLELIC, autosomal or pseudoautosomal	Sources Mackenzie's Mission Expert Review Green Phenotypes Wolfram syndrome, 222300 (3)
Green WFS1 in Deafness_Isolated Level 2: Hearing and ear disorders Version 2.0	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Victorian Clinical Genetics Services Melbourne Genomics Health Alliance Deafness Flagship Melbourne Genomics Health Alliance Deafness Flagship Victorian Clinical Genetics Services Expert Review Green Phenotypes Deafness, autosomal dominant 6/14/38, MIM# 600965 Wolfram syndrome 1 222300 Wolfram-like syndrome, autosomal dominant, MIM# 614296
Green WFS1 in Prepair 1000+ Level 2: Screening Version 3.0	1 review	BIALLELIC, autosomal or pseudoautosomal	Sources Mackenzie's Mission Expert Review Green Phenotypes Wolfram syndrome 1 MIM#222300
Green WFS1 in Transplant Co-Morbidity Level 2: Screening Version 1.0	0 reviews	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources NHS GMS Expert Review Green Phenotypes diabetes insipidus or optic atrophy ?Cataract 41,116400 Wolfram syndrome, 222300 Deafness,autosomal dominant 6/14/38, 600965 {Diabetes mellitus, noninsulin-dependent, association with}, 125853 {Diabetes mellitus, noninsulin-dependent,association with} Deafness, autosomal dominant 6/14/38, 600965 Wolfram-like syndrome, autosomal dominant, 614296