TP53:Ensemblv90

tumor protein p53
OMIM: 191170, ClinGen, DECIPHER

14 panels

Panel Reviews Mode of inheritance Details
14 panels

Amber TP53 in Bone Marrow Failure


Level 2: Haematological disorders
Version 1.131

Component of the following Super Panels:

  • Immunological disorders_SuperPanel
  • 1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • Expert list
    Phenotypes
    • Bone marrow failure syndrome 5, MIM# 618165

    Green TP53 in Incidentalome


    Version 0.370

    1 review Unknown
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green TP53 in Cancer Predisposition_Paediatric


    Level 2: Cancer
    Version 0.132

    0 reviews Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green TP53 in Additional findings_Adult


    Level 2: Screening
    Version 1.130

    1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance
    Phenotypes
    • Li-Fraumeni syndrome, MIM# 151623

    Green TP53 in Wilms Tumour Predisposition


    Level 2: Cancer predisposition
    Version 0.40

    0 reviews Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Red TP53 in CGC_86


    Version 0.3

    0 reviews Other
    Sources
    • CGC_86
    Phenotypes
    • Li-Fraumeni syndrome 1

    Red TP53 in NCGC


    Version 0.3

    0 reviews Other
    Sources
    • NCGC
    Phenotypes
    • Li-Fraumeni syndrome 1

    Red TP53 in TCGA_PANCAN_2018


    Version 0.3

    0 reviews Other
    Sources
    • TCGA_PANCAN_2018
    Phenotypes
    • Li-Fraumeni syndrome 1

    Green TP53 in Medulloblastoma


    Level 2: Cancer Predisposition
    Version 1.1

    1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • SA Pathology
    Phenotypes
    • Medulloblastoma, MONDO:0007959
    • Li-Fraumeni syndrome, MONDO:0018875
    • Li-Fraumeni syndrome, MIM#151623

    Green TP53 in Sarcoma


    Level 2: Cancer susceptibility
    Version 0.4

    0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • SA Pathology

    Green TP53 in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • BabySeq Category A gene
    • Expert Review Green
    Phenotypes
    • Li-Fraumeni syndrome

    Amber TP53 in Incidentalome_PREGEN_DRAFT


    Version 0.43

    1 review Unknown
    Sources
    • Expert Review Amber
    • NSW Health Pathology

    Green TP53 in Genomic newborn screening: BabyScreen+


    Level 2: Screening
    Version 1.141

    1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • BabySeq Category A gene
    Phenotypes
    • Li-Fraumeni syndrome MIM#151623
    Tags
    • cancer
    • treatable

    Green TP53 in Transplant Co-Morbidity


    Level 2: Screening
    Version 0.20

    0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance
    Phenotypes
    • Li-Fraumeni syndrome, MIM# 151623