TP53

tumor protein p53
OMIM: 191170, ClinGen, DECIPHER

10 panels

Panel Reviews Mode of inheritance Details
10 panels

Amber TP53 in Bone Marrow Failure


Level 2: Haematological disorders
Version 2.0

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert list
  • Expert Review Amber
Phenotypes
  • Bone marrow failure syndrome 5, MIM# 618165

Green TP53 in Incidentalome


Version 1.0

1 review Unknown
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Melbourne Genomics Health Alliance
  • Expert Review Green

Green TP53 in Cancer Predisposition_Paediatric


Level 2: Cancer
Version 1.0

0 reviews Unknown
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services

Green TP53 in Additional findings_Adult


Level 2: Screening
Version 2.0

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Melbourne Genomics Health Alliance
  • Expert Review Green
Phenotypes
  • Li-Fraumeni syndrome, MIM# 151623

Green TP53 in Wilms Tumour Predisposition


Level 2: Cancer predisposition
Version 1.0

0 reviews Unknown
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services

Red TP53 in CGC_86


Version 1.0

0 reviews Other
Sources
  • CGC_86
Phenotypes
  • Li-Fraumeni syndrome 1

Green TP53 in Medulloblastoma


Level 2: Cancer Predisposition
Version 2.0

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • SA Pathology
  • Expert Review Green
Phenotypes
  • Medulloblastoma, MONDO:0007959
  • Li-Fraumeni syndrome, MONDO:0018875
  • Li-Fraumeni syndrome, MIM#151623

Green TP53 in Sarcoma


Level 2: Cancer susceptibility
Version 1.0

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • SA Pathology
  • Expert Review Green

Green TP53 in Genomic newborn screening: BabyScreen+


Level 2: Screening
Version 2.0

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • BabySeq Category A gene
  • Expert Review Green
Phenotypes
  • Li-Fraumeni syndrome MIM#151623
Tags
  • cancer
  • treatable

Green TP53 in Transplant Co-Morbidity


Level 2: Screening
Version 1.0

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Melbourne Genomics Health Alliance
  • Expert Review Green
Phenotypes
  • Li-Fraumeni syndrome, MIM# 151623