PanelApp (test)
  1. Genes and Genomic Entities
  2. FLCN:Ensemblv90

FLCN:Ensemblv90

folliculin
OMIM: 607273, ClinGen, DECIPHER

19 panels

Panel Reviews Mode of inheritance Details
19 panels

Green FLCN in Mendeliome


Version 1.3802

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Birt-Hogg-Dube syndrome (MIM#135150)
  • Pneumothorax, primary spontaneous (MIM#173600)

Green FLCN in Renal Macrocystic Disease


Level 2: Renal and urinary tract disorders
Version 0.100

Component of the following Super Panels:

  • Kidneyome_SuperPanel
  • Renal Cystic Disease_SuperPanel

    		•  1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    Phenotypes
    • Birt-Hogg-Dube syndrome, MIM# 135150

    Green FLCN in Additional findings_Adult


    Level 2: Screening
    Version 1.130

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Birt-Hogg-Dube syndrome (MIM#135150)

    Red FLCN in CGC_86


    Version 0.3

    		0 reviews Other
    Sources
    • CGC_86
    Phenotypes
    • Birt-Hogg-Dub syndrome

    Red FLCN in NCGC


    Version 0.3

    		0 reviews Other
    Sources
    • NCGC
    Phenotypes
    • Birt-Hogg-Dub syndrome

    Red FLCN in TCGA_PANCAN_2018


    Version 0.3

    		0 reviews Other
    Sources
    • TCGA_PANCAN_2018
    Phenotypes
    • Birt-Hogg-Dub syndrome

    Green FLCN in Renal cancer


    Level 2: Cancer susceptibility
    Version 0.5

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • SA Pathology
    Phenotypes
    • Renal carcinoma

    Green FLCN in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • BabySeq Category A gene
    • Expert Review Green
    Phenotypes
    • Birt-Hogg-Dube syndrome

    Green FLCN in Incidentalome_PREGEN_DRAFT


    Version 0.43

    		0 reviews Unknown
    Sources
    • NSW Health Pathology
    • Expert Review Green

    Red FLCN in Genomic newborn screening: BabyScreen+


    Level 2: Screening
    Version 1.141

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • BabySeq Category A gene
    Phenotypes
    • Birt-Hogg-Dube syndrome, MIM# 135150

    Green FLCN in Pneumothorax

    Level 3: Structural lung disorders
    Level 2: Respiratory disorders
    Version 1.1

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Emory Genetics Laboratory
    • Radboud University Medical Center, Nijmegen
    • Illumina TruGenome Clinical Sequencing Services
    • Expert list
    • NHS GMS
    • Expert Review Green
    • UKGTN
    • Eligibility statement prior genetic testing
    • Literature
    Phenotypes
    • Pneumothorax, primary spontaneous, OMIM:173600
    • Birt-Hogg-Dube Syndrome, OMIM:135150

    Green FLCN in Facial papules


    Level 2: Dermatological disorders
    Version 1.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Birt-Hogg-Dube syndrome MONDO:0007607

    Green FLCN in Renal Macrocystic Disease


    Level 2: Renal and urinary tract disorders
    Version 1.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review
    • Expert Review Green
    Phenotypes
    • Birt-Hogg-Dube syndrome, MIM# 135150

    Green FLCN in Additional findings_Adult


    Level 2: Screening
    Version 2.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert list
    • Expert Review Green
    Phenotypes
    • Birt-Hogg-Dube syndrome (MIM#135150)

    Red FLCN in TCGA_PANCAN_2018


    Version 1.0

    		0 reviews Other
    Sources
    • TCGA_PANCAN_2018
    Phenotypes
    • Birt-Hogg-Dub syndrome

    Green FLCN in Renal cancer


    Level 2: Cancer susceptibility
    Version 1.0

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • SA Pathology
    • Expert Review Green
    Phenotypes
    • Renal carcinoma

    Green FLCN in Additional findings_Paediatric


    Level 2: Screening
    Version 1.0

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • BabySeq Category A gene
    Phenotypes
    • Birt-Hogg-Dube syndrome

    Green FLCN in Pneumothorax

    Level 3: Structural lung disorders
    Level 2: Respiratory disorders
    Version 2.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Literature
    • Eligibility statement prior genetic testing
    • UKGTN
    • Expert Review Green
    • NHS GMS
    • Expert list
    • Illumina TruGenome Clinical Sequencing Services
    • Radboud University Medical Center, Nijmegen
    • Emory Genetics Laboratory
    Phenotypes
    • Pneumothorax, primary spontaneous, OMIM:173600
    • Birt-Hogg-Dube Syndrome, OMIM:135150

    Green FLCN in Facial papules


    Level 2: Dermatological disorders
    Version 2.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert list
    • Expert Review Green
    Phenotypes
    • Birt-Hogg-Dube syndrome MONDO:0007607