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Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v1.0 RHEB Gene migrated from ENSG00000106615 to ENSG00000106615 (gene set migration)
Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v0.50 RHEB Zornitza Stark Marked gene: RHEB as ready
Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v0.50 RHEB Zornitza Stark Gene: rheb has been classified as Amber List (Moderate Evidence).
Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v0.50 RHEB Zornitza Stark Classified gene: RHEB as Amber List (moderate evidence)
Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v0.50 RHEB Zornitza Stark Gene: rheb has been classified as Amber List (Moderate Evidence).
Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly v0.49 RHEB Zornitza Stark gene: RHEB was added
gene: RHEB was added to Tuberous Sclerosis_Focal Cortical Dysplasia_Hemimegalencephaly. Sources: Literature
somatic tags were added to gene: RHEB.
Mode of inheritance for gene: RHEB was set to Other
Publications for gene: RHEB were set to 41940182; 35687047
Phenotypes for gene: RHEB were set to Focal cortical dysplasia, MONDO:0019009, RHEB-related
Review for gene: RHEB was set to AMBER
Added comment: Somatic mosaic RHEB variants causing focal cortical dysplasia type IIa/IIb were reported in two independent individuals (PMIDs 41940182, 35687047)
Sources: Literature