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Date	Panel	Item	Activity
Filter activities 33 actions
05 Jun 2026	Mendeliome v2.0	IFNG	Gene migrated from ENSG00000111537 to ENSG00000111537 (gene set migration)
31 Oct 2025	Mendeliome v1.3512	IFNGR2	Zornitza Stark edited their review of gene: IFNGR2: Added comment: PMID 23161749: some evidence that haploinsufficiency causes mono-allelic disease. Amber for this association.; Changed publications: 15924140, 18625743, 31222290, 23161749, 23161749; Changed mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
24 Oct 2025	Mendeliome v1.3470	IFNGR2	Zornitza Stark Publications for gene: IFNGR2 were set to 15924140; 18625743; 31222290
24 Oct 2025	Mendeliome v1.3469	IFNGR2	Zornitza Stark edited their review of gene: IFNGR2: Added comment: PMID 23161749: single case report of heterozygous LoF variant causing disease (but ?missed second hit).; Changed publications: 15924140, 18625743, 31222290, 23161749
16 Dec 2024	Mendeliome v1.2217	IFNG	Bryony Thompson Publications for gene: IFNG were set to 32163377
16 Dec 2024	Mendeliome v1.2216	IFNG	Bryony Thompson Classified gene: IFNG as Amber List (moderate evidence)
16 Dec 2024	Mendeliome v1.2216	IFNG	Bryony Thompson Gene: ifng has been classified as Amber List (Moderate Evidence).
16 Dec 2024	Mendeliome v1.2215	IFNG	Bryony Thompson reviewed gene: IFNG: Rating: AMBER; Mode of pathogenicity: None; Publications: 32163377, 38363432; Phenotypes: inherited susceptibility to mycobacterial diseases MONDO:0019146; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
15 Mar 2022	Mendeliome v0.11422	IFNGR2	Zornitza Stark Marked gene: IFNGR2 as ready
15 Mar 2022	Mendeliome v0.11422	IFNGR2	Zornitza Stark Gene: ifngr2 has been classified as Green List (High Evidence).
15 Mar 2022	Mendeliome v0.11422	IFNGR2	Zornitza Stark Phenotypes for gene: IFNGR2 were changed from to Immunodeficiency 28, mycobacteriosis, MIM# 614889
15 Mar 2022	Mendeliome v0.11421	IFNGR2	Zornitza Stark Publications for gene: IFNGR2 were set to
15 Mar 2022	Mendeliome v0.11420	IFNGR2	Zornitza Stark Mode of inheritance for gene: IFNGR2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
15 Mar 2022	Mendeliome v0.11419	IFNGR2	Zornitza Stark reviewed gene: IFNGR2: Rating: GREEN; Mode of pathogenicity: None; Publications: 15924140, 18625743, 31222290; Phenotypes: Immunodeficiency 28, mycobacteriosis, MIM# 614889; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
15 Mar 2022	Mendeliome v0.11419	IFNGR1	Zornitza Stark Marked gene: IFNGR1 as ready
15 Mar 2022	Mendeliome v0.11419	IFNGR1	Zornitza Stark Gene: ifngr1 has been classified as Green List (High Evidence).
15 Mar 2022	Mendeliome v0.11419	IFNGR1	Zornitza Stark Phenotypes for gene: IFNGR1 were changed from to Immunodeficiency 27A, mycobacteriosis, AR, MIM# 209950; Immunodeficiency 27B, mycobacteriosis, AD, MIM# 615978
15 Mar 2022	Mendeliome v0.11418	IFNGR1	Zornitza Stark Publications for gene: IFNGR1 were set to
15 Mar 2022	Mendeliome v0.11417	IFNGR1	Zornitza Stark Mode of inheritance for gene: IFNGR1 was changed from Unknown to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
15 Mar 2022	Mendeliome v0.11416	IFNGR1	Zornitza Stark reviewed gene: IFNGR1: Rating: GREEN; Mode of pathogenicity: None; Publications: 7815885, 8960475, 9389728, 10811850, 10192386, 12244188, 15589309; Phenotypes: Immunodeficiency 27A, mycobacteriosis, AR, MIM# 209950, Immunodeficiency 27B, mycobacteriosis, AD, MIM# 615978; Mode of inheritance: BOTH monoallelic and biallelic, autosomal or pseudoautosomal
02 Aug 2020	Mendeliome v0.3634	IFNG	Zornitza Stark Phenotypes for gene: IFNG were changed from Mendelian susceptibility to mycobacterial disease to Mendelian susceptibility to mycobacterial disease; Immunodeficiency 69, MIM#618963
02 Aug 2020	Mendeliome v0.3633	IFNG	Zornitza Stark edited their review of gene: IFNG: Changed phenotypes: Mendelian susceptibility to mycobacterial disease, Immunodeficiency 69, MIM#618963
30 Apr 2020	Mendeliome v0.2673	IFNG	Zornitza Stark Marked gene: IFNG as ready
30 Apr 2020	Mendeliome v0.2673	IFNG	Zornitza Stark Gene: ifng has been classified as Red List (Low Evidence).
30 Apr 2020	Mendeliome v0.2673	IFNG	Zornitza Stark Phenotypes for gene: IFNG were changed from to Mendelian susceptibility to mycobacterial disease
30 Apr 2020	Mendeliome v0.2672	IFNG	Zornitza Stark Publications for gene: IFNG were set to
30 Apr 2020	Mendeliome v0.2671	IFNG	Zornitza Stark Mode of inheritance for gene: IFNG was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
30 Apr 2020	Mendeliome v0.2670	IFNG	Zornitza Stark Classified gene: IFNG as Red List (low evidence)
30 Apr 2020	Mendeliome v0.2670	IFNG	Zornitza Stark Gene: ifng has been classified as Red List (Low Evidence).
30 Apr 2020	Mendeliome v0.2669	IFNG	Zornitza Stark reviewed gene: IFNG: Rating: RED; Mode of pathogenicity: None; Publications: 32163377; Phenotypes: Mendelian susceptibility to mycobacterial disease; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
17 Nov 2019	Mendeliome v0.0	IFNGR2	Zornitza Stark gene: IFNGR2 was added gene: IFNGR2 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: IFNGR2 was set to Unknown
17 Nov 2019	Mendeliome v0.0	IFNGR1	Zornitza Stark gene: IFNGR1 was added gene: IFNGR1 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: IFNGR1 was set to Unknown
17 Nov 2019	Mendeliome v0.0	IFNG	Zornitza Stark gene: IFNG was added gene: IFNG was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: IFNG was set to Unknown